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In the shadow of St. Louis' Gateway Arch on the banks of the mighty Mississippi River, you'll find this quiet suburban community. Our Columbia hotel is conveniently located adjacent to I-255, less than 15 miles from downtown St. Louis and minutes from southern St. Louis County. Discover Columbia's small-town Midwestern charm when you stay at our Hampton Inn St. Louis-Columbia hotel.
See historic landmarks and visit the 60-story Gateway Arch. After a day of exploring the Contemporary Art Museum, touring the Anheuser-Busch Brewery and cheering on the Cardinals or Rams, drive out of the hustle and bustle and back to the relaxing calm of our Columbia hotel.
Make yourself at home in a comfy guest room and watch TV or stay connected with free WiFi. Start your day right with Hampton’s free hot breakfast, and make sure you try our delicious waffles. If you’re in a rush, make sure to take a healthy Hampton On the Run® Breakfast Bag, available Monday through Friday. Catch up with work in our free business center or host a meeting for up to 40 people. After a long day, rejuvenate in our free fitness center or take a dip in our indoor pool.