Update your password regularly to keep your account safe.
Skip brand navigation
Where are you going?
City, airport, address, attraction, or hotel
Use HHonors Points
Use flexible dates
AAA rate *
AARP rate *
CARP rate *
Government / Military rates *
* ID required at check-in
close tab panel
Find where we are located
View the Maps & Directions Page
This content will open in a overlay
Save up to 15% when you book at least 14 days early.*
Skip secondary navigation
Welcome to the Hampton Inn Muscatine hotel. We are located 35 minutes from Quad City Airport on the banks of the Mississippi River. Discover shops and cafés with tranquil river views in downtown Muscatine, just three miles away. Whether visiting for business or leisure, our friendly and attentive staff will ensure you have a memorable stay at our Muscatine, Iowa hotel.
Feel at home in a comfy guest room featuring a large work desk or convenient lap desk. Watch a favorite show on the 32-inch flat-screen HDTV or unwind on a clean and fresh Hampton bed®. Rooms with two beds are perfect for families, or choose rooms with king-sized beds to stretch out and relax. Accessible rooms offer maximum comfort for special needs guests. Enjoy in-room amenities such as 32-inch flat-screen HDTVs, free WiFi, coffeemakers, mini refrigerators and microwaves.
Wake up refreshed and start your day right with Hampton’s free hot breakfast, and make sure you try our delicious waffles. Even if you're in a rush, simply grab one of our free Hampton On the Run® Breakfast Bags, available Monday through Friday, for a quick, healthy meal to go. Catch up with work in the 24-hour business center or host a meeting in our well-equipped Hawkeye Meeting Room. Work out in our free 24-hour fitness center or unwind in the indoor swimming pool and whirlpool.