Hampton by Hilton

skip form

Where are you going?

Rooms Adults (18+) Children
Room 2:
Room 3:
Room 4:
Room 5:
Room 6:
Room 7:
Room 8:
Room 9:

Special Rates

* ID required at check-in

Find it   Check Rooms & Rates *Best Price Guarantee
Reward Category: 4
Hotel Information
3:00 pm
11:00 am
$250 USD fee will be assessed for smoking in a non-smoking room. The smokers oasis is located northwest of the front entrance of the hotel.
Self parking: (Free Parking)
Valet: Not Available
Service animals allowed: Yes
Pets allowed: No
Where we are static map image

Find where we are located
View the Maps & Directions Page

Saint Louis,MO Local Weather

This content will open in a overlay

Five Day Forecast

Hampton Inn & Suites St. Louis/South I-55

4200 MidAmerica Lane, Saint Louis, Missouri, 63129, USA TEL: +1-314-894-1900 FAX: +1-314-894-0063

Hotel Details

Feel right at home at our hotel near St. Louis. Appreciate the combination of a location convenient to downtown St. Louis and caring Midwest hospitality that makes a stay at our hotel a memorable experience. Find all the business tools you need to stay connected on the road and enjoy the personal touches, and child-friendly amenities that go towards making a good stay great.

Start each day with Hampton’s free hot breakfast or grab a free, healthy Hampton On the Run® Breakfast Bag to take along with you, available Monday to Friday. Stay in touch with your office or family while you’re on the road in the useful business center and take advantage of free high-speed internet access in each guest room. Stay fit in the modern fitness center to maintain your workout regimen and enjoy a stress relieving swim in the indoor heated pool and whirlpool. We have everything you need for a wonderful stay right here at our St. Louis hotel.

TripAdvisor Hall of Fame Winner

Our hotel is now in the TripAdvisor Hall of Fame! Our staff takes great pride in offering an exceptional guest experience and being recognized with the TripAdvisor Certificate of Excellence for outstanding traveler reviews five years in a row.

TripAdvisor Travelers' Choice Award 2015

Hampton Inn & Suites St. Louis/South I-55 won the TripAdvisor Travelers’ Choice® award for 2015 in the Top 25 Bargain Hotels in the United States category. The honor is based on millions of traveler reviews and opinions related to niche and geographic categories. Stay with us and discover why our Mehlville, Missouri hotel ranks in the top 1% of the 748,000 hotels reviewed.

This content will open in a overlay

100% Hampton
100% Hampton

100% Hampton Guarantee®

Friendly service, clean rooms, comfortable surroundings, every time. If you're not satisfied, we don't expect you to pay. That's our commitment & your guarantee. That's 100% Hampton.

Our 100% Hampton Guarantee® is boldly etched on our front desk so that it is constantly visible to our employees and our guests. Our guarantee epitomizes the pride we take in our brand, our hotels and our service to you, our guest. We'll do whatever it takes to make our guests feel welcome, relaxed and completely comfortable.