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Hotel Information
3:00 pm
11:00 am
$250 USD fee will be assessed for smoking in a non-smoking room. The smokers oasis is located northwest of the front entrance of the hotel.
Self parking: (Free Parking)
Valet: Not Available
Service animals allowed: Yes
Pets allowed: No
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Hampton Inn & Suites St. Louis/South I-55

4200 MidAmerica Lane, Saint Louis, Missouri, 63129, USA TEL: +1-314-894-1900 FAX: +1-314-894-0063

Rooms & Suites

Experience Midwest hospitality with our lodging in St. Louis, MO. Feel refreshed with a peaceful night's rest in a clean, fresh bed. Stay connected with free high-speed internet access. Relax in front of a large, flat screen TV and wake up to your favorite songs on the MP3 player compatible alarm clock.

  • Hampton Inn & Suites St. Louis/South I-55 Hotel, MO - 2 Queen Beds Non-Smoking

    Guest Rooms

    Our promise to you includes a clean, comfortable hotel room. In fact, we have 92 of them! If you're traveling with your family, you may opt for a room with two beds. Or, if you're here by yourself on business, why not book a room with a plush, king-sized bed so you can stretch out and relax?

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  • Hampton Inn & Suites St. Louis/South I-55 Hotel, MO - 1 King Bed Studio Suite


    Looking for some extra room to stretch out and relax? Our suites are spacious, comfortable and convenient. Check out our various options below.

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  • Hampton Inn & Suites St. Louis/South I-55 Hotel, MO - 1 King Accessible Bed Non-Smoking

    Accessible Rooms

    We've designed our accessible hotel rooms to make our guests with disabilities - as well as friends and family who accompany them - more comfortable. Click on the links below for more information. The corresponding photo may not reflect the specific accessible room type or room feature.

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100% Hampton