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Experience the delightful mix of Old World charm and Midwest hospitality in the vibrant city of St. Louis when you stay at our Hampton Inn & Suites St Louis/South I-55 hotel. Be greeted by an incredibly attentive and accommodating staff that rivals many hotels. Enjoy easy access to downtown to visit the city’s signature Gateway Arch. Ride the tram to the top, where 32 windows offer spectacular views of this ‘Gateway to the West’ city.
Located near downtown St. Louis, our hotel is convenient to many attractions and businesses. Explore museums or visit the St. Louis Zoo. Attend a baseball game at Busch Stadium, home of the St. Louis Cardinals. Tour the famous Anheuser-Busch Brewery. Savor the best of Italian food in the Hill neighborhood, or visit the Soulard neighborhood for jazz and blues clubs, as well as the Soulard Farmer’s Market.
Retreat to one of our 92 St. Louis hotel rooms to rest in a clean and fresh Hampton bed®. Join us each morning for Hampton’s free hot breakfast. Even if you're in a rush, simply grab one of our free Hampton On the Run® Breakfast Bags, available Monday through Friday, for a quick, healthy meal to go. You'll also find great business services, free WiFi, and recreational facilities for a truly enjoyable stay at our St. Louis hotel.
2013 Connie Award Winner