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Find a cozy hotel in historic Missouri at Hampton Inn Cape Girardeau. Just off the I-55, you’ll find the Hampton Inn Cape Girardeau hotel at the heart of this charming city. With 39 historic sites on the National Register, Cape Girardeau was once the busiest steamboat port on the Mississippi River. These days, you can watch riverboats dock from Riverfront Park, visit the Fort D historic site and enjoy browsing the many antique stores of well-preserved downtown Cape Girardeau, MO.
Relax in a comfortable guest room featuring a clean and fresh Hampton beds®. Accessible rooms are designed with generous door and furniture clearances for easy movement. Stay connected in your hotel room in Cape Girardeau, MO with free high-speed internet access. Maintain your exercise routine with the cardio equipment and weights in our fitness center during your stay at our Cape Girardeau hotel.
Start your day right with a Hampton free hot breakfast – choose fresh waffles, hot oatmeal, and fresh fruit. If you’re in a rush on weekdays, we’ll give you a Hampton On the Run™ breakfast bag to go. Ask our local experts – the friendly Hampton Inn Cape Girardeau hotel team – for Cape Girardeau, MO restaurant recommendations.