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Experience charming and historic St. Charles, MO during your stay at the Hampton Inn St. Louis/St. Charles hotel, 25 miles from St. Louis, Missouri. Stroll the brick-lined streets, lunch in a Victorian house or browse for antiques and unique gifts in a Main Street boutique. Celebrate frontier heritage at the site where explorers Lewis and Clark met before their expedition. Dine at Lewis & Clark, an American restaurant and public house located in an historic three-story home with outdoor patio overlooking the Missouri River and Main Street.
Enjoy classic American fare at Miss Aimee B's Tea Room before shopping at The Upstairs Marketplace. Tour Missouri wineries including Balducci Vineyards, Little Hills Winery, and Yellow Farmhouse Winery just minutes from the St. Charles, MO hotel. Our 122-room hotel is less than two miles from Lindenwood University. Visit the famous Gateway Arch or the St. Louis Museum of Art located in an historic Beaux-Art building.
Whether you’re staying at our St. Charles, Missouri hotel on business or planning a weekend getaway in charming historic St. Charles, enjoy comfortable guest rooms with free high-speed internet access and 32-inch flat-screen TVs during your stay. Finish a presentation for tomorrow's meeting at our large work desk. Our lap desk makes it convenient to check your emails while you relax in your Hampton clean and fresh bed®.