skip form

Where are you going?

Rooms Adults (18+) Children
Room 2:
Room 3:
Room 4:
Room 5:
Room 6:
Room 7:
Room 8:
Room 9:

(AAA, AARP, etc)

* ID required at check-in

Find it   Check Rooms & Rates Our Best Rates Guarantee
Reward Category: 5
Hotel Information
3:00 pm
12:00 pm
A fee of up to 250 USD will be assessed for smoking in a non-smoking room. Please ask the Front Desk for locations of designated outdoor smoking areas.
Self parking:
Valet: Not Available
Service animals allowed: Yes
Pets allowed: No
Where we are static map image

Find where we are located
View the Maps & Directions Page

Self parking
Valet parking
Not Available
Not Available
Not Available
In/Out Privileges
Not Available
Other Parking Information
parking lot
Hampton Inn & Suites - Family on Vacation Book Early and Save!

Save up to 15% when you book at least 14 days early.

View Offer Details


Hampton Inn Buffalo-Williamsville

5455 Main Street, Williamsville, New York, 14221, USA TEL: +1-716-632-0900 FAX: +1-716-632-1300

Maps & Directions

5455 Main Street , Williamsville, NY, 14221, US

Route Results

Distance From Hotel:
Travel Time:
Send To: Email

Directions from the Hotel Staff

From I-90 - Take Exit 50, 290W-Niagara Falls to Exit 7B-Main St. Hampton Inn Williamsville is located one half mile down on the right side behind Rite Aid.

From Airport - Turn right out of the airport onto Genesee St. Make a right at the first light-Cayuga Rd. Approximately two miles down turn left onto Main St. At the first light turn left onto Los Robles and the hotel is located on the right side.

From Downtown Buffalo - Follow East Tupper St. to the 33 East Exwy. Continue on 33 East to I-90 East and follow to 290-towards Niagara Falls. Stay in the right lane and take first exit-7B. Our Williamsville hotel is on the right side about one half mile down behind Rite Aid.

How to Get Here

From the Airport

Greater Buffalo International Airport
Make right onto Genesee Street, right on Cayuga. Go 2 miles to Main St. and make a left. Next light make a left on Los Robles. Hotel is on the right hand side.
Distance from Hotel: 3 mi.
Drive Time: 5 min.
Type Typical Minimum Charge
Courtesy Bus Call hotel for hours.
Taxi 15.00 USD
Get Turn-by-Turn Directions
Distance from Hotel:
Travel Time:
Greater Rochester International Airport
390 South to 90 West. 290 West to Exit 7B, Main Street East.
Distance from Hotel: 80 mi.
Drive Time: 90 min.
Get Turn-by-Turn Directions
Distance from Hotel:
Travel Time:
Lester B. Pearson International Airport
401 South to QEW west to Peace Bridge. 190 North to 290 East to Exit 7B Main Street East.
Distance from Hotel: 100 mi.
Drive Time: 2 hr.
Get Turn-by-Turn Directions
Distance from Hotel:
Travel Time:

100% Hampton