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Hotel Information

3:00 pm
11:00 am
A fee of up to 250.00 USD will be accessed for smoking in a non-smoking room. please ask the front desk for locations of designated outdoor smoking areas.
Self parking: (Free On-site Parking)
Valet: Not Available
Service animals allowed: Yes
Pets allowed: No

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Hampton Inn Poplar Bluff

2420 Crestwood Drive, Poplar Bluff, Missouri, 63901, USA TEL: +1-573-300-4550 FAX: +1-573-300-4540
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At a Glance

modern hotel near the best of Poplar Bluff, MO.

Set in the rolling hills of southeast Missouri, at the Gateway to the Ozarks, the brand new Hampton Inn Poplar Bluff hotel is conveniently located off Highway 67 - the major highway that connects St. Louis, Missouri to Little Rock, Arkansas. The hotel is ideally situated in a quiet, residential setting, but is only minutes from Three Rivers College and lots of exciting shopping options. Guests can also enjoy easy access to some of the best restaurants, local heritage sites and sports facilities in southeast Missouri.

Take a dip in the sparkling indoor swimming pool, or work out in the modern fitness center. After a busy day, retire to your spacious guest room to enjoy a variety of modern amenities. Stay connected with free WiFi at the ergonomic desk, or lie back on the clean and fresh Hampton bed®, and watch movies on the flat-screen TV. Choose one of our comfortable suites for more space and a plush sofa bed – perfect for families and extended-stays.

Join us each morning at Hampton’s free hot breakfast buffet, where you can enjoy a variety of hot and cold favorites, including our famous fresh-baked waffles. If you are heading out early, grab a free Hampton’s On the Run Breakfast Bag™, Monday – Friday, for a convenient, healthy meal to go. Plan your next meeting at this Poplar Bluff hotel in our 780 sq. ft. meeting room, and stay productive in the 24-hour business center.

About the Hotel

Hotel Facts

  • Poplar Bluff hotel near US 60, on Hwy 67 South
  • Less than three miles from the city center
  • Within walking distance of Three Rivers College
  • Minutes from Poplar Bluff Industrial Park
  • Less than two miles from Poplar Bluff Regional Medical Center

Rooms & Suites

Included in Every Stay

  • Free hot breakfast
  • Clean and fresh Hampton bed®
  • Free WiFi in every room
  • Gym/fitness center use


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100% Hampton
100% Hampton

100% Hampton Guarantee®

Making you happy makes us happy. So, if we can make your stay better, talk to any member of our team, and we'll make sure you're 100% happy. GUARANTEED.™