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Hotel Information

3:00 pm
11:00 am
A fee of up to 250 USD will be assessed for smoking on property.
Self parking:
Valet: Not Available
Service animals allowed: Yes
Pets allowed: No

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Military Discount

Save up to 15%

Active & retired military and their families enjoy exclusive savings of up to 15% off at Hampton.

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Hampton Inn Santee-I-95

9060 Old Number Six Highway, Santee, South Carolina, 29142, USA TEL: +1-803-854-2444 FAX: +1-803-854-5906
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At a Glance

a cozy retreat in Santee, SC on the edge of Lake Marion.

The Hampton Inn hotel in Santee, SC is located near Lake Marion and five golf courses. Take in the beauty of Santee State Park, commune with nature at the Santee National Wildlife Refuge or go fishing, boating, or swimming on Lake Marion – it's all just outside the door at our Santee hotel. Captain’s Quarters is within walking distance, and it's a short drive to Clark’s Restaurant - both are locals’ favorites. Golf any time at the Lake Marion Country Club, Santee National, Santee Resort and several others. Our hotel in Santee also puts you within easy reach of historical sites such as Eutaw Springs Battlefield.

Discover what makes Hampton Inn Santee-I-95 unique among Santee, SC hotels. Unwind in a spacious guest room and enjoy modern comforts to help you feel at home. Stay connected with free internet access and work in comfort with a practical lap desk. Enjoy our King rooms’ sofa bed and cocktail tables, allowing you to stretch out and fully relax. Take advantage of our double queen bedrooms, which offer a sitting area. Enjoy great value during your stay in our outdoor swimming pool and gym. Catch up with work in the business center and host meetings for up to 30 guests in our 576 sq. ft. multi-function event room.

The hotel is able to accommodate boat trailers and RVs in our extended parking lot, with power connections available to guests.

About The Hotel

Hotel Facts

  • Ideally located near beautiful Lake Marion and things to do in Santee, SC
  • Three local golf courses and the historic Eutaw Springs Battlefield
  • Boat and RV parking with power connections
  • 81 spacious Santee, SC hotel rooms including accessible rooms
  • Outdoor swimming pool
  • Flexible Santee, SC meeting space accommodating up to 30 guests

Rooms & Suites

Included in Every Stay

  • Free hot breakfast
  • Clean and fresh Hampton bed®
  • Free high-speed wired and wireless internet access in every room
  • Gym/fitness center use


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100% Hampton
100% Hampton

100% Hampton Guarantee®

Making you happy makes us happy. So, if we can make your stay better, talk to any member of our team, and we'll make sure you're 100% happy. GUARANTEED.™

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Senior Savings

Save up to 10%

All Hampton guests age 65+ can save up to 10% off our Best Available Rate when booking online.

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